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Hegedűs Csaba

Hegedűs Csaba
University of Debrecen Faculty of Medicine
Department of Medical Chemistry

Publication list

Tudóstér co-authors statistics filterable publication list
Uploaded publications:
45
Publications in DEA:
45
OA:
27
Date range:
2007-2025
2025
1.
Óvári, I., Pluzsnyik, É., Kiss, R., Lelesz, B., Hegedűs, C., Leiter, I., Erdei, T. D., Viczján, G., Szilvássy, Z., Juhász, B., Gesztelyi, R.: Effects of Lutein and Zeaxanthin on Endothelial Function in Aging Sprague-Dawley Rats.
In: Programme Oral & Poster Abstracts - International Pharmacology Conference : focus on drug discovery and innovation : HUPHAR 2025 Mátraháza 4-6, June. Kiadta: a Magyar Kísérletes és Klinikai Farmakológiai Társaság, HUPHAR, [S.l.], 190, 2025.
DEA
2.
Gaál, R., Lelesz, B., Leiter, I., Badale, A., Pelles-Taskó, B., Hegedűs, C., Szilvássy, Z., Juhász, B., Jurca, T., Burlou-Nagy, C., Pallag, A., Kiss, R.: Evaluation of the Therapeutic Potential of Anthocyanin-Rich Sour-Cherry (Prunus Cerasus) Extract Topical Formulation in an Imiquimod-Induced Psoriasis Model in Rats.
In: Programme Oral & Poster Abstracts - International Pharmacology Conference : focus on drug discovery and innovation : HUPHAR 2025 Mátraháza 4-6, June. Kiadta: a Magyar Kísérletes és Klinikai Farmakológiai Társaság, HUPHAR, [S.l.], 161, 2025.
DEA
3.
Leiter, I., Pelles-Taskó, B., Hegedűs, C., Szilvássy, Z., Németh, J., Juhász, B., Lelesz, B., Kiss, R.: Somatostatin as a Regulatory Neuropeptide: Physiological Roles and Quantification Using a Novel RIA Method.
In: Programme Oral & Poster Abstracts - International Pharmacology Conference : focus on drug discovery and innovation : HUPHAR 2025 Mátraháza 4-6, June. Kiadta: a Magyar Kísérletes és Klinikai Farmakológiai Társaság, HUPHAR, [S.l.], 198, 2025.
DEA
4.
Bede, Á. M., Váróczy, C., Polgár, Z., Fazekas, G., Hegedűs, C., Kókai, E., Kovács, K., Virág, L.: The autophagy inhibitor bafilomycin inhibits antibody-dependent natural killer cell-mediated killing of breast carcinoma cells.
Int. J. Mol. Sci. 26, 1-19, (article identifier: 6273), 2025.
doi DEA WoS Scopus
Journal metrics:
Q1 Catalysis
Q1 Computer Science Applications
D1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
D1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
2024
5.
Sturniolo, I., Váróczy, C., Regdon, Z., Türk-Mázló, A., Muzsai, S., Bácsi, A., Intili, G., Hegedűs, C., Boothby, M. R., Holechek, J., Ferraris, D., Schüler, H., Virág, L.: PARP14 contributes to the development of the tumor-associated macrophage phenotype.
Int. J. Mol. Sci. 25 (7), 1-21, (article identifier: 3601), 2024.
doi DEA WoS Scopus
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
Q1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
D1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
6.
Sturniolo, I., Váróczy, C., Bede, Á. M., Hegedűs, C., Demény, M. Á., Virág, L.: Quantifying antibody-dependent cellular cytotoxicity in a tumor spheroid model: application for drug discovery.
J. Vis. Exp. 206, 1-14, (article identifier: 65922), 2024.
doi DEA WoS Scopus
Journal metrics:
Q3 Biochemistry, Genetics and Molecular Biology (miscellaneous)
Q2 Chemical Engineering (miscellaneous)
Q3 Immunology and Microbiology (miscellaneous)
Q3 Neuroscience (miscellaneous)
2023
7.
Guti, E., Bede, Á. M., Váróczy, C., Hegedűs, C., Demény, M. Á., Virág, L.: High-Content Screening Assay for the Identification of Antibody-Dependent Cellular Cytotoxicity Modifying Compounds.
JoVE. 198, 1-12, (article identifier: 64485), 2023.
doi DEA WoS Scopus
Journal metrics:
Q3 Biochemistry, Genetics and Molecular Biology (miscellaneous)
Q2 Chemical Engineering (miscellaneous)
Q3 Immunology and Microbiology (miscellaneous)
Q3 Neuroscience (miscellaneous)
8.
Ujlaki, G., Kovács, T., Vida, A., Kókai, E., Rauch, B., Schwarcz, S., Mikó, E., Janka, E. A., Sipos, A., Hegedűs, C., Uray, K., Nagy, P., Bai, P.: Identification of bacterial metabolites modulating breast cancer cell proliferation and epithelial-mesenchymal transition.
Molecules. 28 (15), 1-18, (article identifier: 5898), 2023.
doi DEA WoS Scopus
Journal metrics:
Q1 Analytical Chemistry
Q1 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
9.
Ráduly, Z., Szabó, L., Dienes, B., Szentesi, P., Bana, Á. V., Hajdú, T., Kókai, E., Hegedűs, C., Csernoch, L., Gönczi, M.: Migration of Myogenic Cells Is Highly Influenced by Cytoskeletal Septin7.
Cells. 12 (14), 1825, (article identifier: 1825), 2023.
doi DEA WoS Scopus
Journal metrics:
Q1 Biochemistry, Genetics and Molecular Biology (miscellaneous)
2022
10.
Hajnády, Z., Nagy-Pénzes, M., Demény, M. Á., Kovács, K., El-Hamoly, T., Maléth, J., Hegyi, P. J., Polgár, Z., Hegedűs, C., Virág, L.: OGG1 Inhibition Reduces Acinar Cell Injury in a Mouse Model of Acute Pancreatitis.
Biomedicines. 10 (10), 1-17, (article identifier: 2543), 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Biochemistry, Genetics and Molecular Biology (miscellaneous)
Q1 Medicine (miscellaneous)
11.
Guti, E., Regdon, Z., Sturniolo, I., Kiss, A., Kovács, K., Demény, M. Á., Szöőr, Á., Vereb, G., Szöllősi, J., Hegedűs, C., Polgár, Z., Virág, L.: The multitargeted receptor tyrosine kinase inhibitor sunitinib induces resistance of HER2 positive breast cancer cells to trastuzumab-mediated ADCC.
Cancer Immunol. Immunother. 71 (9), 2151-2168, 2022.
doi DEA WoS Scopus
Journal metrics:
Q1 Cancer Research
Q1 Immunology
Q1 Immunology and Allergy
D1 Medicine (miscellaneous)
Q1 Oncology
12.
Nagy-Pénzes, M., Hajnády, Z., Regdon, Z., Demény, M. Á., Kovács, K., El-Hamoly, T., Maléth, J., Hegyi, P. J., Hegedűs, C., Virág, L.: Tricetin Reduces Inflammation and Acinar Cell Injury in Cerulein-Induced Acute Pancreatitis: the Role of Oxidative Stress-Induced DNA Damage Signaling.
Biomedicines. 10 (6), 1-20, (article identifier: 1371), 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Biochemistry, Genetics and Molecular Biology (miscellaneous)
Q1 Medicine (miscellaneous)
2021
13.
Regdon, Z., Demény, M. Á., Kovács, K., Hajnády, Z., Nagy-Pénzes, M., Bakondi, E., Kiss, A., Hegedűs, C., Virág, L.: High-Content Screening identifies inhibitors of oxidative stress-induced parthanatos: cytoprotective and anti-inflammatory effects of ciclopirox.
Br. J. Pharmacol. 178 (5), 1095-1113, 2021.
doi DEA WoS Scopus
Journal metrics:
D1 Pharmacology
14.
Kiss, A., Csikos, C., Regdon, Z., Polgár, Z., Virág, L., Hegedűs, C.: NMNAT1 Is a Survival Factor in Actinomycin D-Induced Osteosarcoma Cell Death.
Int. J. Mol. Sci. 22 (16), 1-17, (article identifier: 8869), 2021.
doi DEA WoS Scopus
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
Q1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
15.
El-Hamoly, T., Hajnády, Z., Nagy-Pénzes, M., Bakondi, E., Regdon, Z., Demény, M. Á., Kovács, K., Hegedűs, C., Abd El-Rahman, S. S., Szabó, É., Maléth, J., Hegyi, P. J., Virág, L.: Poly(ADP-Ribose) Polymerase 1 Promotes Inflammation and Fibrosis in a Mouse Model of Chronic Pancreatitis.
Int. J. Mol. Sci. 22 (7), 1-15, (article identifier: 3593), 2021.
doi DEA WoS Scopus
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
Q1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
2020
16.
Kiss, B. K., Szántó, M., Hegedűs, C., Antal, D., Szödényi, A., Márton, J., Méhes, G., Virág, L., Szegedi, A., Bai, P.: Poly(ADP-ribose) polymerase-1 depletion enhances the severity of inflammation in an imiquimod-induced model of psoriasis.
Exp. Dermatol. 29 (1), 79-85, 2020.
doi DEA WoS Scopus
Journal metrics:
Q2 Biochemistry
Q1 Dermatology
Q2 Molecular Biology
17.
Kiss, A., Ráduly, A. P., Regdon, Z., Polgár, Z., Tarapcsák, S., Sturniolo, I., El-Hamoly, T., Virág, L., Hegedűs, C.: Targeting nuclear NAD+ synthesis inhibits DNA repair, impairs metabolic adaptation increases chemosensitivity of U-2OS osteosarcoma cells.
Cancers (Basel). 12 (5), 1-27, (article identifier: 1180), 2020.
DEA WoS Scopus
Journal metrics:
Q2 Cancer Research
Q1 Oncology
2019
18.
Kovács, P., Csonka, T., Kovács, T., Sári, Z., Ujlaki, G., Sipos, A., Karányi, Z., Szeőcs, D., Hegedűs, C., Uray, K., Jankó, L., Kiss, M., Kiss, B. K., Laoui, D., Virág, L., Méhes, G., Bai, P., Mikó, E.: Lithocholic acid, a metabolite of the microbiome, increases oxidative stress in breast cancer.
Cancers (Basel). 11, 1-31, (article identifier: 1255), 2019.
doi DEA WoS Scopus
Journal metrics:
Q1 Cancer Research
Q1 Oncology
19.
Regdon, Z., Robaszkiewicz, A., Kovács, K., Rygielska, Ż., Hegedűs, C., Bodoor, K., Szabó, É., Virág, L.: LPS protects macrophages from AIF-independent parthanatos by downregulation of PARP1 expression, induction of SOD2 expression, and a metabolic shift to aerobic glycolysis.
Free Radic. Biol. Med. 131, 184-196, 2019.
doi DEA
Journal metrics:
Q1 Biochemistry
Q1 Physiology (medical)
20.
Robinson, N., Ganesan, R., Hegedűs, C., Kovács, K., Kufer, T. A., Virág, L.: Programmed necrotic cell death of macrophages: Focus on pyroptosis, necroptosis, and parthanatos.
Redox Biol. 26, 1-8, (article identifier: 101239), 2019.
doi DEA WoS Scopus
Journal metrics:
Q1 Biochemistry
D1 Clinical Biochemistry
D1 Organic Chemistry
21.
Bakondi, E., Singh, S. B., Hajnády, Z., Nagy-Pénzes, M., Regdon, Z., Kovács, K., Hegedűs, C., Madácsy, T., Maléth, J., Hegyi, P. J., Demény, M. Á., Nagy, T., Kéki, S., Szabó, É., Virág, L.: Spilanthol Inhibits Inflammatory Transcription Factors and iNOS Expression in Macrophages and Exerts Anti-inflammatory Effects in Dermatitis and Pancreatitis.
Int. J. Mol. Sci. 20 (17), 1-18, (article identifier: 4308), 2019.
doi DEA WoS Scopus
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
Q1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
Q1 Spectroscopy
2018
22.
Hegedűs, C., Kovács, K., Lakatos, P., Virág, L.: A poli(ADP-ribóz) polimerázok (PARP): fókuszban a PARP-1.
In: Ezerarcú fehérjék. Szerk.: Buday László, Nyitray László, Perczel András, Semmelweis Kiadó, 2018, 775-786, 2018. ISBN: 9789633314586
DEA
23.
Hegedűs, C., Kovács, K., Polgár, Z., Regdon, Z., Szabó, É., Robaszkiewicz, A., Forman, H. J., Martner, A., Virág, L.: Redox control of cancer cell destruction.
Redox Biol. 16, 59-74, 2018.
doi DEA WoS Scopus
Journal metrics:
Q1 Biochemistry
D1 Clinical Biochemistry
D1 Organic Chemistry
24.
Bodnár, E., Bakondi, E., Kovács, K., Hegedűs, C., Lakatos, P., Robaszkiewicz, A., Regdon, Z., Virág, L., Szabó, É.: Redox Profiling Reveals Clear Differences between Molecular Patterns of Wound Fluids from Acute and Chronic Wounds.
Oxid. Med. Cell. Longev. 2018, 1-12, 2018.
doi DEA
Journal metrics:
Q2 Aging
Q1 Biochemistry
Q2 Cell Biology
Q1 Medicine (miscellaneous)
2017
25.
Bátori, R. K., Bécsi, B., Nagy, D., Kónya, Z., Hegedűs, C., Bordán, Z., Verin, A., Lontay, B., Erdődi, F.: Interplay of myosin phosphatase and protein phosphatase-2A in the regulation of endothelial nitric-oxide synthase phosphorylation and nitric oxide production.
Sci Rep. 7 (44698), 1-17, (article identifier: 44698), 2017.
doi DEA WoS Scopus
Journal metrics:
D1 Multidisciplinary
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