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Somsák László

Somsák László
University of Debrecen Faculty of Science and Technology
Institute of Chemistry
Department of Organic Chemistry

Publication list

Tudóstér co-authors statistics filterable publication list
Uploaded publications:
211
Publications in DEA:
189
OA:
76
Date range:
1982-2025
2025
1.
Akel, R., Kacsir, I., Kerekes, É., Freytag, C., Szoták, E., Boros-Pál, D., Janka, E. A., Bényei, A., Kardos, G., Bokor, É., Somsák, L., Bai, P., Sipos, A., Kun, S.: Platinum-group metal half-sandwich complexes of sugar-isoxazol(in)e conjugates - synthesis and evaluation of their antineoplastic and antimicrobial activities.
Eur. J. Pharm. Sci. [Epub ahead of print], 1-44, (article identifier: 107260), 2025.
doi DEA
Journal metrics:
Q1 Pharmaceutical Science (2024)
2.
Akel, R., Zaki, A. I., Kerekes, É., Kacsir, I., Kiss, G. A., Freytag, C., Szoták, E., Boros-Pál, D., Janka, E. A., Kardos, G., Bai, P., Somsák, L., Kun, S., Sipos, A., Bokor, É.: Platinum-group metal half-sandwich complexes with C-glucopyranosyl 1,2,3-triazoles and isoxazoles as ligands: synthesis and evaluation as antineoplastic and antimicrobial agents.
Eur. J. Pharm. Sci. [Epub ahead of print], 1-51, (article identifier: 107259), 2025.
doi DEA
Journal metrics:
Q1 Pharmaceutical Science (2024)
3.
Zaki, A. I., Sipos, A., Kacsir, I., Kovács, N. I., Kerekes, É., Szoták, E., Freytag, C., Demény, M. Á., Révész, I., Buglyó, P., Bényei, A., Janka, E. A., Kardos, G., Somsák, L., Bai, P., Bokor, É.: Platinum-group metal-sandwich complexes of 1-(alpa-D-glucopyranosyl)-4-hetaryl-1,2,3-triazoles: synthesis, solution equilibrium studies and investigation of their anticancer and antimicrobial activities.
Front. Chem. 13, 1-23, (article identifier: 1619991), 2025.
doi DEA
Journal metrics:
Q1 Chemistry (miscellaneous) (2024)
2024
4.
Homolya, L., Mathomes, R. T., Varga, L., Docsa, T., Juhász, L., Hayes, J. M., Somsák, L.: Synthesis, in silico and kinetics evaluation of N-(beta-D-glucopyranosyl)-2-arylimidazole-4(5)-carboxamides and N-(beta-D-glucopyranosyl)-4(5)-arylimidazole-2-carboxamides as glycogen phosphorylase inhibitors.
Int. J. Mol. Sci. 25 (9), 1-21, (article identifier: 4591), 2024.
doi DEA WoS Scopus
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
Q1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
D1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
2023
5.
József, J., Somsák, L., Tóth, M., Juhász, L.: [2+2] Cycloadditions of Methylene exo-Glycals: Synthesis of Glycopyranosylidene-Spiro-Azetidine-2-ones (beta-Lactams) and Cyclobutanones.
Eur. J. Org. Chem. 26 (12), 1-10, (article identifier: 202201488), 2023.
doi DEA WoS Scopus
Journal metrics:
Q2 Organic Chemistry
Q2 Physical and Theoretical Chemistry
6.
Juhász-Tóth, É., Malecz, Á. S., Tóth, M., Homolya, Á., Kaszás, T., Somsák, L., Juhász, L.: 2-Iodo-1-C-acceptor-substituted glycals: synthesis and transformation into 1,2-C,Cdisubstituted glycals via Suzuki-Miyaura coupling reaction.
New J. Chem. 47 (42), 19376-19388, 2023.
doi DEA WoS Scopus
Journal metrics:
Q3 Catalysis
Q2 Chemistry (miscellaneous)
Q2 Materials Chemistry
7.
Homolya, Á., Jedlóczki, I., Ábrahám, A., Somsák, L., Tóth, M., Juhász, L.: Behaviour of some 1-C-acceptor-substituted glycals under azidohydroxylation conditions.
Carbohydr. Res. 529, 1-12, (article identifier: 108825), 2023.
doi DEA WoS Scopus
Journal metrics:
Q2 Analytical Chemistry
Q3 Biochemistry
Q3 Medicine (miscellaneous)
Q2 Organic Chemistry
8.
Kun, S., Mathomes, R. T., Docsa, T., Somsák, L., Hayes, J. M.: Design and Synthesis of 3-(β-D-Glucopyranosyl)-4-amino/4-guanidino Pyrazole Derivatives and Analysis of Their Glycogen Phosphorylase Inhibitory Potential.
Molecules. 28 (7), 1-19, (article identifier: 3005), 2023.
doi DEA WoS Scopus
Journal metrics:
Q1 Analytical Chemistry
Q1 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
9.
József, J., Somsák, L., Juhász, L.: Exo-glikál származékok átalakításainak a vizsgálata: tioladdíciós és cikloaddíciós reakciók.
Magy. Kém. F. 129 (3-4), 147-154, 2023.
doi DEA
10.
Bokor, É., Kecskés, D., Gombás, F., Fehér, A., Kardos, E., Dabian, A., Vonza, Z., Szennyes, E., Somsák, L.: First representatives of C-glycosyl 1,2,4,5-tetrazines: synthesis of 3-beta-d-glucopyranosyl 1,2,4,5-tetrazines and their transformation into 3-beta-d-glucopyranosyl pyridazines.
New Journal of Chemistry 47 (1), 56-74, 2023.
doi DEA WoS Scopus
Journal metrics:
Q3 Catalysis
Q2 Chemistry (miscellaneous)
Q2 Materials Chemistry
11.
Kacsir, I., Sipos, A., Kiss, T., Major, E., Bajusz, N., Tóth, E., Buglyó, P., Somsák, L., Kardos, G., Bai, P., Bokor, É.: Half sandwich-type osmium, ruthenium, iridium and rhodium complexes with bidentate glycosyl heterocyclic ligands induce cytostasis in platinum-resistant ovarian cancer cells and bacteriostasis in Gram-positive multiresistant bacteria.
Front. Chem. 11, 1-18, (article identifier: 1086267), 2023.
doi DEA WoS Scopus
Journal metrics:
Q1 Chemistry (miscellaneous)
12.
Kacsir, I., Sipos, A., Major, E., Bajusz, N., Bényei, A., Buglyó, P., Somsák, L., Kardos, G., Bai, P., Bokor, É.: Half-sandwich type platinum-group metal complexes of C-Glucosaminyl azines: syntheses, antineoplastic and antimicrobial activities.
Molecules. 28 (7), 1-55, (article identifier: 3058), 2023.
doi DEA WoS Scopus
Journal metrics:
Q1 Analytical Chemistry
Q1 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
13.
Lázár, L., Tsagkarakou, A. S., Stravodimos, G. A., Kontopidis, G., Leffler, H., Nilsson, U. J., Somsák, L., Leonidas, D. D.: Strong Binding of C-Glycosylic1,2-Thiodisaccharides to Galectin-3 - Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds.
Journal of Medicinal Chemistry 66 (17), 12420-12431, 2023.
doi DEA WoS Scopus
Journal metrics:
D1 Drug Discovery
D1 Molecular Medicine
2022
14.
Kiss, M., Timári, I., Barna, T., Mészáros, Z., Slámová, K., Bojarová, P., Křen, V., Hayes, J. M., Somsák, L.: 2-Acetamido-2-deoxy-d-glucono-1,5-lactone Sulfonylhydrazones: Synthesis and Evaluation as Inhibitors of Human OGA and HexB Enzymes.
Int. J. Mol. Sci. 23 (3), 1-18, (article identifier: 1037), 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
D1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
15.
Kaszás, T., Szakács, B., Juhász-Tóth, É., Cservenyák, I., Kovács, T., Juhász, L., Somsák, L., Tóth, M.: Coupling of N-Tosylhydrazones with Tetrazoles: A Regioselective Synthesis of 2,5-Disubstituted-2H- Tetrazoles.
European Journal of Organic Chemistry 2022 (42), e202201103, (article identifier: 202201103), 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Organic Chemistry
Q2 Physical and Theoretical Chemistry
16.
Kaszás, T., Baráth, B. Á., Balázs, B., Blága, T., Juhász, L., Somsák, L., Tóth, M.: Coupling Reactions of Anhydro-Aldose Tosylhydrazones with Boronic Acids.
Molecules. 27 (6), 1-31, (article identifier: 1795), 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Analytical Chemistry
Q2 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
17.
Bokor, É., Ferenczi, A., Hashimov, M., Juhász-Tóth, É., Götz, Z., Zaki, A. I., Somsák, L.: First Synthesis of 3-Glycopyranosyl-1,2,4-Triazines and Some Cycloadditions There of.
Molecules. 27 (22), 1-16, (article identifier: 7801), 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Analytical Chemistry
Q2 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
18.
Kánya, N., Kun, S., Somsák, L.: Glycopyranosylidene-Spiro-Morpholinones: Evaluation of the Synthetic Possibilities Based on Glyculosonamide Derivatives and a New Method for the Construction of the Morpholine Ring.
Molecules. 27 (22), 1-18, (article identifier: 7785), 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Analytical Chemistry
Q2 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
19.
Homolya, L., Antal, D., Nagy, M., Juhász-Tóth, É., Tóth, M., Bényei, A., Somsák, L., Juhász, L.: Reactions of 1-C-acceptor-substituted glycals with nucleophiles under acid promoted (Ferrier-rearrangement) conditions.
Carbohydr. Res. 519, 1-10, (article identifier: 108582), 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Analytical Chemistry
Q3 Biochemistry
Q3 Medicine (miscellaneous)
Q3 Organic Chemistry
20.
Kacsir, I., Sipos, A., Bényei, A., Janka, E. A., Buglyó, P., Somsák, L., Bai, P., Bokor, É.: Reactive Oxygen Species Production Is Responsible for Antineoplastic Activity of Osmium, Ruthenium, Iridium and Rhodium Half-Sandwich Type Complexes with Bidentate Glycosyl Heterocyclic Ligands in Various Cancer Cell Models.
Int. J. Mol. Sci. 23 (2), 1-39, (article identifier: 813), 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
D1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
21.
Balázs, B., Tóth, Z., Kacsir, I., Sipos, A., Buglyó, P., Somsák, L., Bokor, É., Kardos, G., Bai, P.: Targeting multiresistant Gram-positive bacteria by ruthenium, osmium, iridium and rhodium half-sandwich type complexes with bidentate monosaccharide ligands.
Front. Chem. 10, 1-9, (article identifier: 868234), 2022.
doi DEA WoS Scopus
Journal metrics:
Q1 Chemistry (miscellaneous)
2021
22.
Kaszás, T., Cservenyák, I., Juhász-Tóth, É., Kulcsár, A., Granatino, P., Nilsson, U. J., Somsák, L., Tóth, M.: Coupling of N-tosylhydrazones with tetrazoles: synthesis of 2-beta-d-glycopyranosylmethyl-5-substituted-2H-tetrazole type glycomimetics.
Org. Biomol. Chem. 19 (3), 605-618, 2021.
doi DEA WoS Scopus
Journal metrics:
Q2 Biochemistry
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
23.
Sipos, Á., Szennyes, E., Hajnal, É., Kun, S., Szabó, E. K., Uray, K., Somsák, L., Docsa, T., Bokor, É.: Dual-Target Compounds against Type 2 Diabetes Mellitus: proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors.
Pharmaceuticals. 14 (4), 1-27, 2021.
doi DEA WoS Scopus
Journal metrics:
Q1 Drug Discovery
Q2 Molecular Medicine
Q1 Pharmaceutical Science
24.
Homolya, L., Juhász, L., Somsák, L.: Halogen addition to some 1-C-substituted pyranoid glycals.
Carbohydr. Res. 504, 1-11, (article identifier: 108292), 2021.
doi DEA
Journal metrics:
Q3 Analytical Chemistry
Q3 Biochemistry
Q3 Medicine (miscellaneous)
Q3 Organic Chemistry
25.
Kiss, M., Szabó, E., Bocska, B., Sinh, L. T., Fernandes, C. P., Timári, I., Hayes, J. M., Somsák, L., Barna, T.: Nanomolar inhibition of human OGA by 2-acetamido-2-deoxy-d-glucono-1,5-lactone semicarbazone derivatives.
Eur. J. Med. Chem. 223, 1-14, (article identifier: 113649), 2021.
doi DEA WoS Scopus
Journal metrics:
Q1 Drug Discovery
Q1 Medicine (miscellaneous)
Q1 Organic Chemistry
Q1 Pharmacology
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