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Somsák László

Somsák László
University of Debrecen Faculty of Science and Technology
Institute of Chemistry
Department of Organic Chemistry

Publication list

Tudóstér co-authors statistics filterable publication list
Uploaded publications:
197
Publications in DEA:
175
OA:
76
Date range:
1982-2024
2024
1.
Homolya, L., Mathomes, R. T., Varga, L., Docsa, T., Juhász, L., Hayes, J. M., Somsák, L.: Synthesis, in silico and kinetics evaluation of N-(beta-D-glucopyranosyl)-2-arylimidazole-4(5)-carboxamides and N-(beta-D-glucopyranosyl)-4(5)-arylimidazole-2-carboxamides as glycogen phosphorylase inhibitors.
Int. J. Mol. Sci. 25 (9), 1-21, (article identifier: 4591), 2024.
doi DEA WoS Scopus
Journal metrics:
Q2 Catalysis (2023)
Q1 Computer Science Applications (2023)
D1 Inorganic Chemistry (2023)
Q1 Medicine (miscellaneous) (2023)
Q2 Molecular Biology (2023)
D1 Organic Chemistry (2023)
Q1 Physical and Theoretical Chemistry (2023)
D1 Spectroscopy (2023)
2023
2.
József, J., Somsák, L., Tóth, M., Juhász, L.: [2+2] Cycloadditions of Methylene exo-Glycals: Synthesis of Glycopyranosylidene-Spiro-Azetidine-2-ones (beta-Lactams) and Cyclobutanones.
Eur. J. Org. Chem. 26 (12), 1-10, (article identifier: 202201488), 2023.
doi DEA WoS Scopus
Journal metrics:
Q2 Organic Chemistry
Q2 Physical and Theoretical Chemistry
3.
Juhász-Tóth, É., Malecz, Á. S., Tóth, M., Homolya, Á., Kaszás, T., Somsák, L., Juhász, L.: 2-Iodo-1-C-acceptor-substituted glycals: synthesis and transformation into 1,2-C,Cdisubstituted glycals via Suzuki-Miyaura coupling reaction.
New J. Chem. 47 (42), 19376-19388, 2023.
doi DEA WoS Scopus
Journal metrics:
Q3 Catalysis
Q2 Chemistry (miscellaneous)
Q2 Materials Chemistry
4.
Homolya, Á., Jedlóczki, I., Ábrahám, A., Somsák, L., Tóth, M., Juhász, L.: Behaviour of some 1-C-acceptor-substituted glycals under azidohydroxylation conditions.
Carbohydr. Res. 529, 1-12, (article identifier: 108825), 2023.
doi DEA WoS Scopus
Journal metrics:
Q2 Analytical Chemistry
Q3 Biochemistry
Q3 Medicine (miscellaneous)
Q2 Organic Chemistry
5.
Kun, S., Mathomes, R. T., Docsa, T., Somsák, L., Hayes, J. M.: Design and Synthesis of 3-(β-D-Glucopyranosyl)-4-amino/4-guanidino Pyrazole Derivatives and Analysis of Their Glycogen Phosphorylase Inhibitory Potential.
Molecules. 28 (7), 1-19, (article identifier: 3005), 2023.
doi DEA WoS Scopus
Journal metrics:
Q1 Analytical Chemistry
Q1 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
6.
József, J., Somsák, L., Juhász, L.: Exo-glikál származékok átalakításainak a vizsgálata: tioladdíciós és cikloaddíciós reakciók.
Magy. Kém. F. 129 (3-4), 147-154, 2023.
doi DEA
7.
Bokor, É., Kecskés, D., Gombás, F., Fehér, A., Kardos, E., Dabian, A., Vonza, Z., Szennyes, E., Somsák, L.: First representatives of C-glycosyl 1,2,4,5-tetrazines: synthesis of 3-beta-d-glucopyranosyl 1,2,4,5-tetrazines and their transformation into 3-beta-d-glucopyranosyl pyridazines.
New Journal of Chemistry 47 (1), 56-74, 2023.
doi DEA WoS Scopus
Journal metrics:
Q3 Catalysis
Q2 Chemistry (miscellaneous)
Q2 Materials Chemistry
8.
Kacsir, I., Sipos, A., Kiss, T., Major, E., Bajusz, N., Tóth, E., Buglyó, P., Somsák, L., Kardos, G., Bai, P., Bokor, É.: Half sandwich-type osmium, ruthenium, iridium and rhodium complexes with bidentate glycosyl heterocyclic ligands induce cytostasis in platinum-resistant ovarian cancer cells and bacteriostasis in Gram-positive multiresistant bacteria.
Front. Chem. 11, 1-18, (article identifier: 1086267), 2023.
doi DEA WoS Scopus
Journal metrics:
Q1 Chemistry (miscellaneous)
9.
Kacsir, I., Sipos, A., Major, E., Bajusz, N., Bényei, A., Buglyó, P., Somsák, L., Kardos, G., Bai, P., Bokor, É.: Half-sandwich type platinum-group metal complexes of C-Glucosaminyl azines: syntheses, antineoplastic and antimicrobial activities.
Molecules. 28 (7), 1-55, (article identifier: 3058), 2023.
doi DEA WoS Scopus
Journal metrics:
Q1 Analytical Chemistry
Q1 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
10.
Lázár, L., Tsagkarakou, A. S., Stravodimos, G. A., Kontopidis, G., Leffler, H., Nilsson, U. J., Somsák, L., Leonidas, D. D.: Strong Binding of C-Glycosylic1,2-Thiodisaccharides to Galectin-3 - Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds.
Journal of Medicinal Chemistry 66 (17), 12420-12431, 2023.
doi DEA WoS Scopus
Journal metrics:
D1 Drug Discovery
D1 Molecular Medicine
2022
11.
Kiss, M., Timári, I., Barna, T., Mészáros, Z., Slámová, K., Bojarová, P., Křen, V., Hayes, J. M., Somsák, L.: 2-Acetamido-2-deoxy-d-glucono-1,5-lactone Sulfonylhydrazones: Synthesis and Evaluation as Inhibitors of Human OGA and HexB Enzymes.
Int. J. Mol. Sci. 23 (3), 1-18, (article identifier: 1037), 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
D1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
12.
Kaszás, T., Szakács, B., Juhász-Tóth, É., Cservenyák, I., Kovács, T., Juhász, L., Somsák, L., Tóth, M.: Coupling of N-Tosylhydrazones with Tetrazoles: A Regioselective Synthesis of 2,5-Disubstituted-2H- Tetrazoles.
European Journal of Organic Chemistry 2022 (42), e202201103, 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Organic Chemistry
Q2 Physical and Theoretical Chemistry
13.
Kaszás, T., Baráth, B. Á., Balázs, B., Blága, T., Juhász, L., Somsák, L., Tóth, M.: Coupling Reactions of Anhydro-Aldose Tosylhydrazones with Boronic Acids.
Molecules. 27 (6), 1-31, 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Analytical Chemistry
Q2 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
14.
Bokor, É., Ferenczi, A., Hashimov, M., Juhász-Tóth, É., Götz, Z., Zaki, A. I., Somsák, L.: First Synthesis of 3-Glycopyranosyl-1,2,4-Triazines and Some Cycloadditions There of.
Molecules. 27 (22), 1-16, 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Analytical Chemistry
Q2 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
15.
Kánya, N., Kun, S., Somsák, L.: Glycopyranosylidene-Spiro-Morpholinones: Evaluation of the Synthetic Possibilities Based on Glyculosonamide Derivatives and a New Method for the Construction of the Morpholine Ring.
Molecules. 27 (22), 1-18, 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Analytical Chemistry
Q2 Chemistry (miscellaneous)
Q2 Drug Discovery
Q2 Medicine (miscellaneous)
Q3 Molecular Medicine
Q2 Organic Chemistry
Q1 Pharmaceutical Science
Q2 Physical and Theoretical Chemistry
16.
Homolya, L., Antal, D., Nagy, M., Juhász-Tóth, É., Tóth, M., Bényei, A., Somsák, L., Juhász, L.: Reactions of 1-C-acceptor-substituted glycals with nucleophiles under acid promoted (Ferrier-rearrangement) conditions.
Carbohydr. Res. 519, 1-10, 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Analytical Chemistry
Q3 Biochemistry
Q3 Medicine (miscellaneous)
Q3 Organic Chemistry
17.
Kacsir, I., Sipos, A., Bényei, A., Janka, E. A., Buglyó, P., Somsák, L., Bai, P., Bokor, É.: Reactive Oxygen Species Production Is Responsible for Antineoplastic Activity of Osmium, Ruthenium, Iridium and Rhodium Half-Sandwich Type Complexes with Bidentate Glycosyl Heterocyclic Ligands in Various Cancer Cell Models.
Int. J. Mol. Sci. 23 (2), 1-39, (article identifier: 813), 2022.
doi DEA WoS Scopus
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
D1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
18.
Balázs, B., Tóth, Z., Kacsir, I., Sipos, A., Buglyó, P., Somsák, L., Bokor, É., Kardos, G., Bai, P.: Targeting multiresistant Gram-positive bacteria by ruthenium, osmium, iridium and rhodium half-sandwich type complexes with bidentate monosaccharide ligands.
Front. Chem. 10, 1-9, 2022.
doi DEA WoS Scopus
Journal metrics:
Q1 Chemistry (miscellaneous)
2021
19.
Kaszás, T., Cservenyák, I., Juhász-Tóth, É., Kulcsár, A., Granatino, P., Nilsson, U. J., Somsák, L., Tóth, M.: Coupling of N-tosylhydrazones with tetrazoles: synthesis of 2-beta-d-glycopyranosylmethyl-5-substituted-2H-tetrazole type glycomimetics.
Org. Biomol. Chem. 19 (3), 605-618, 2021.
doi DEA WoS Scopus
Journal metrics:
Q2 Biochemistry
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
20.
Sipos, Á., Szennyes, E., Hajnal, É., Kun, S., Szabó, E. K., Uray, K., Somsák, L., Docsa, T., Bokor, É.: Dual-Target Compounds against Type 2 Diabetes Mellitus: proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors.
Pharmaceuticals. 14 (4), 1-27, 2021.
doi DEA WoS Scopus
Journal metrics:
Q1 Drug Discovery
Q2 Molecular Medicine
Q1 Pharmaceutical Science
21.
Homolya, L., Juhász, L., Somsák, L.: Halogen addition to some 1-C-substituted pyranoid glycals.
Carbohydr. Res. 504, 1-11, 2021.
doi DEA
Journal metrics:
Q3 Analytical Chemistry
Q3 Biochemistry
Q3 Medicine (miscellaneous)
Q3 Organic Chemistry
22.
Kiss, M., Szabó, E., Bocska, B., Sinh, L. T., Fernandes, C. P., Timári, I., Hayes, J. M., Somsák, L., Barna, T.: Nanomolar inhibition of human OGA by 2-acetamido-2-deoxy-d-glucono-1,5-lactone semicarbazone derivatives.
Eur. J. Med. Chem. 223, 1-14, 2021.
doi DEA WoS Scopus
Journal metrics:
Q1 Drug Discovery
Q1 Medicine (miscellaneous)
Q1 Organic Chemistry
Q1 Pharmacology
23.
Kacsir, I., Sipos, A., Ujlaki, G., Buglyó, P., Somsák, L., Bai, P., Bokor, É.: Ruthenium half-sandwich type complexes with bidentate monosaccharide ligands show antineoplastic activity in ovarian cancer cell models through reactive oxygen species production.
Int. J. Mol. Sci. 221, 1-41, 2021.
doi DEA WoS Scopus
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
Q1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
D1 Spectroscopy
24.
Tsagkarakou, A. S., Chasapi, S. A., Koulas, S. M., Tsialtas, I., Kyriakis, E., Drakou, C. E., Kun, S., Somsák, L., Spyroulias, G. A., Psarra, A. M. G., Leonidas, D. D.: Structure activity relationship of the binding of p-coumaroyl glucose to glycogen phosphorylase and its effect on hepatic cell metabolic pathways.
European Journal of Medicinal Chemistry Reports. 3, 1-11, 2021.
doi DEA
2020
25.
Goyard, D., Kónya, B., Czifrák, K., Larini, P., Demontrond, F., Leroy, J., Balzarin, S., Tournier, M., Tousch, D., Petit, P., Duret, C., Maurel, P., Docsa, T., Gergely, P., Somsák, L., Praly, J. P., Azay-Milhau, J., Vidal, S.: Glucose-based spiro-oxathiazoles as in vivo anti-hyperglycemic agents through glycogen phosphorylase inhibition.
Org. Biomol. Chem. 18 (5), 931-940, 2020.
doi DEA WoS Scopus
Journal metrics:
Q2 Biochemistry
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
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