Tóth Béla

University of Debrecen Faculty of Medicine

Department of Medical Chemistry

1979-

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1982-2002

2002

Oikonomakos, N. G., Kosmopoulou, M. N., Zographos, S. E., Leonidas, D. D., Chrysina, E. D., Somsák, L., Nagy, V., Praly, J. P., Docsa, T., Tóth, B., Gergely, P.: Binding of N-acetyl-N'-β-D-glucopyranosyl urea and N-benzoyl-N'-β-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies.
Eur. J. Biochem. 269 (6), 1684-1696, 2002.

doi DEA

Oikonomakos, N. G., Skamnaki, V. T., Ősz, E., Szilágyi, L., Somsák, L., Docsa, T., Tóth, B., Gergely, P.: Kinetic and crystallographic studies of glucopyranosylidene spirothiohydantoin binding to glycogen phosphorylase B.
Bioorg. Med. Chem. 10 (2), 261-268, 2002.

doi DEA

Journal metrics:

Q2 Biochemistry

Q1 Clinical Biochemistry

Q1 Drug Discovery

Q3 Molecular Biology

Q2 Molecular Medicine

Q2 Organic Chemistry

Q1 Pharmaceutical Science

2001

Docsa, T., Somsák, L., Tóth, B., Gergely, P.: Effect of glucopyranosylidene-spiro-thiohydantoin on the enzymes of hepatic glycogen metabolism in rats.
In: Protein Modules in Cellular Signalling. Ed.: by Ludwig Heilmeyer, Peter Friedrich, IOS Press, Amsterdam, 142-149, 2001. ISBN: 1586031805

DEA

Somsák, L., Kovács, L., Tóth, M., Ősz, E., Szilágyi, L., Györgydeák, Z., Dinya, Z., Docsa, T., Tóth, B., Gergely, P.: Synthesis of and a comparative study on the inhibition of muscle and liver glycogen phosphorylases by epimeric pairs of D-Gluco- and D-Xylopyranosylidene-spiro-(thio)hydantoins and N-(D-Glucopyranosyl) amides.
J. Med. Chem. 44 (17), 2843-2848, 2001.

doi DEA

Journal metrics:

D1 Drug Discovery

Q1 Molecular Medicine

2000

Somsák, L., Nagy, V., Docsa, T., Tóth, B., Gergely, P.: Gram-scale synthesis of a glucopyranosylidene-spiro-thiohydantoin and its effect on hepatic glycogen metabolism studied in vitro and in vivo.
Tetrahedron Asymmetry. 11, 405-408, 2000.

DEA

Journal metrics:

Q2 Catalysis

D1 Inorganic Chemistry

D1 Organic Chemistry

Q1 Physical and Theoretical Chemistry

1999

Gergely, P., Murányi, A., Tóth, B., Zákány, R., Módis, L., Erdődi, F.: A foszfoszerin/foszfotreonin-specifikus protein foszfatázokat gátló toxinok élettani hatásai.
In: Nephrologia. Szerk.: Kakuk György, Kárpáti István, Debrecen Airport Travel Kiadó, Debrecen, 13-20, 1999. ISBN: 9630376008

DEA

Ősz, E., Somsák, L., Szilágyi, L., Kovács, L., Docsa, T., Tóth, B., Gergely, P.: Efficient inhibition of muscle and liver glycogen phosphorylases by a new glucopyranosylidene-spiro-thiohydantoin.
Bioorg. Med. Chem. Lett. 9 (10), 1385-1390, 1999.

DEA

Journal metrics:

Q2 Biochemistry

Q1 Clinical Biochemistry

Q1 Drug Discovery

Q3 Molecular Biology

Q2 Molecular Medicine

Q2 Organic Chemistry

D1 Pharmaceutical Science

1996

Bakó, É., Dombrádi, V., Farkas, I., Murányi, A., Szöőr, B., Szűcs, K., Tóth, B., Vissi, E.: Laboratory manual for general, organic and bioorganic chemistry: 1. practical guide.
Department of Medical Chemistry University School of Medicine, Debrecen, 180 p. : ill., 1996.

DEA

Bakó, É., Dombrádi, V., Farkas, I., Murányi, A., Szöőr, B., Szűcs, K., Tóth, B., Vissi, E.: Laboratory manual for general, organic and bioorganic chemistry: 2. workbook.
Department of Medical Chemistry University School of Medicine, Debrecen, 96 p. : ill., 1996.

DEA

1995

10.

Erdődi, F., Hirano, K., Hirano, M., Hartshorne, D. J., Tóth, B., Gergely, P.: Endothall thioanhydride inhibits protein phosphatases-1 and -2A in vivo.
Am. J. Physiol. 269, C1176-C1184, 1995.

DEA

1992

11.

Tóth, B., Zelena, D., Szűcs, K., Szöőr, B., Gergely, P.: Comparative characterization of liver glycogen metabolism in rat and guinea-pig.
Comp. Biochem. Physiol. B-Biochem. Mol. Biol. 103 (3), 547-552, 1992.

DEA

1990

12.

Bollen, M., Miralpeix, M., Ventura, F., Tóth, B., Bartrons, R., Stalmans, W.: Oral administration of vanadate to streptozotocin-diabetic rats restores the glucose-induced activation of liver glycogen synthase.
Biochem. J. 267 (1), 269-271, 1990.

doi DEA WoS Scopus

13.

Stalmans, W., Bollen, M., Tóth, B., Gergely, P.: Short-term hormonal control of protein phosphatases involved in hepatic glycogen metabolism.
Adv. Enzyme Regul. 30, 305-327, 1990.

DEA WoS

1989

14.

Tóth, B., Bollen, M., Stalmans, W.: Decreased activity and impaired hormonal control of protein phosphatases in rat livers with a deficiency of phosphorylase kinase.
Biochem. J. 264 (2), 429-436, 1989.

doi DEA WoS Scopus

1988

15.

Farkas, I., Tóth, B., Vereb, G., Csortos, C., Gergely, P.: Activation/dephosphorylation of rabbit muscle glycogen synthase by the catalytic subunits of protein phosphatase-1 and 2A.
Acta Biochim. Biophys. Hung. 23 (3-4), 231-246, 1988.

DEA

16.

Tóth, B., Bollen, M., Stalmans, W.: Acute regulation of hepatic protein phosphatases by glucagon, insulin, and glucose.
J. Biol. Chem. 263 (28), 14061-14066, 1988.

doi DEA

17.

Farkas, I., Tóth, B., Gergely, P.: Regulation of the dephosphorylation of phosphorylase A by glucose, AMP and polyamines.
Int. J. Biochem. 20 (2), 197-201, 1988.

doi DEA WoS Scopus

1986

18.

Farkas, I., Tóth, B., Bot, G., Gergely, P.: Hormonal regulation of phosphorylase phosphatase activity in rat liver.
FEBS Lett. 203 (2), 253-256, 1986.

doi DEA WoS Scopus

19.

Vereb, G., Erdődi, F., Tóth, B., Bot, G.: Regulatory subunit of type II cAMP-dependent protein-kinase as substrate and inhibitor of protein phosphatase-1 and -2A.
FEBS Lett. 197 (1-2), 139-142, 1986.

doi DEA

1985

20.

Gergely, P., Tóth, B., Farkas, I., Bot, G.: Effect of fructose 1-phosphate on the activation of liver glycogen synthase.
Biochem. J. 232 (1), 133-137, 1985.

doi DEA WoS Scopus

1983

21.

Gergely, P., Matkó, J., Tóth, B., Dombrádi, V., Bot, G.: Heterotropic interactions of AMP and glucose binding sites in phosphorylase a are destroyed by limited proteolysis.
Biochem. Biophys. Res. Commun. 113 (3), 825-831, 1983.

DEA

22.

Dombrádi, V., Tóth, B., Gergely, P., Bot, G.: Limited proteolysis of glycogen phosphorylase a by subtilisin BPN'.
Int. J. Biochem. 15 (11), 1329-1336, 1983.

doi DEA

1982

23.

Dombrádi, V., Hajdu, J., Friedrich, P., Tóth, B., Bot, G.: Interaction of ligands in phosphorylase A as monitored by crosslinking and enzymatic modifications: synergism of glucose and caffeine manifested in the exposure of N-terminal segment.
Int. J. Biochem. 14 (4), 277-284, 1982.

DEA

24.

Kiss, T., Tóth, B.: Microscopic dissociation processes of some tyrosine derivatives.
Talanta. 29 (6), 539-544, 1982.

doi DEA

25.

Bot, G., Kovács, E., Tóth, B., Dombrádi, V., Gergely, P.: Role of fructose-1-phosphate in the regulation of the dephosphorylation of glycogen phosphorylase [alpha].
Acta Biochim. Biophys. Acad. Sci. Hung. 17 (3-4), 183-189, 1982.

DEA