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Széles Lajos István

Széles Lajos István

Publication list

Uploaded publications:
28
Publications in DEA:
28
OA:
13
Date range:
2006-2026
2026
1.
Széles, L., Márton, É., Takács, B., Domoszlai, D., Homoki, E., Göczi, L., Penyige, A., Balogh, I., Szilágyi, M.: Comparative ChIP-Seq Analysis of ERα Binding Induced by Estradiol, Zearalenone, and Bisphenol A in Human Ovarian Cells.
Biomolecules. 16 (10), 1-20, (article identifier: 1392), 2026.
Journal metrics:
Q1 Biochemistry (2025)
Q2 Molecular Biology (2025)
2.
Mianesaz, H., Göczi, L., Bojcsuk, D., Ghalamkari, S., Fadel, L., Póliska, S., Penyige, A., Nagy, L., Nagy, G., Vámosi, G., Széles, L.: Genome-wide chromatin profiling reveals a non-limiting role for RXR in macrophage-like cells stimulated with multiple nuclear receptor agonists.
J. Biol Chem. [Epub ahead of print], 2026.
Journal metrics:
Q1 Biochemistry (2025)
Q1 Cell Biology (2025)
Q1 Molecular Biology (2025)
2025
3.
Mianesaz, H., Göczi, L., Nagy, G., Póliska, S., Fadel, L., Bojcsuk, D., Penyige, A., Szirák, K., AlHaman, F., Nagy, L., Vámosi, G., Széles, L.: Genomic regions occupied by both RARα and VDR are involved in the convergence and cooperation of retinoid and vitamin D signaling pathways.
Nucleic Acids Res. 53 (6), 1-20, (article identifier: 230), 2025.
Journal metrics:
D1 Genetics
2022
4.
Göczi, L., Csumita, M., Horváth, A., Nagy, G., Póliska, S., Pigni, M., Thelemann, C., Dániel, B., Mianesaz, H., Varga, T., Sen, K., Raghav, S. K., Schoggins, J. W., Nagy, L., Acha-Orbea, H., Meissner, F., Reith, W., Széles, L.: A Multi-Omics Approach Reveals Features That Permit Robust and Widespread Regulation of IFN-Inducible Antiviral Effectors.
J. Immun. 209 (10), 1930-1941, 2022.
Journal metrics:
Q1 Immunology
Q1 Immunology and Allergy
2021
5.
Kerekes, V., Sándor, I., Nagy, D., Ozogány, K., Göczi, L., Ibler, B., Széles, L., Barta, Z.: Trends in demography, genetics, and social structure of Przewalski's horses in the Hortobagy National Park, Hungary over the last 22 years.
Glob. Ecol. Conserv. 25, 1-14, (article identifier: 01407), 2021.
Journal metrics:
Q1 Ecology
Q1 Ecology, Evolution, Behavior and Systematics
Q1 Nature and Landscape Conservation
2020
6.
Csumita, M., Csermely, A., Horváth, A., Nagy, G., Monori, F., Göczi, L., Orbea, H. A., Reith, W., Széles, L.: Specific enhancer selection by IRF3, IRF5 and IRF9 is determined by ISRE half-sites, 5' and 3' flanking bases, collaborating transcription factors and the chromatin environment in a combinatorial fashion.
Nucleic Acids Res. 48 (2), 589-604, 2020.
Journal metrics:
D1 Genetics
7.
Márton, É., Beke-Varga, A. E., Széles, L., Göczi, L., Penyige, A., Nagy, B., Szilágyi, M.: The Cell-Free Expression of MiR200 Family Members Correlates with Estrogen Sensitivity in Human Epithelial Ovarian Cells.
Int. J. Mol. Sci. 21 (24), 1-19, (article identifier: 9725), 2020.
Journal metrics:
Q2 Catalysis
D1 Computer Science Applications
D1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
D1 Organic Chemistry
D1 Physical and Theoretical Chemistry
D1 Spectroscopy
2019
8.
Kerekes, V., Ozogány, K., Sándor, I., Végvári, Z., Czető, C., Nyírő, B., Szabados, T., Széles, L., Barta, Z.: Analysis of habitat use, activity, and body condition scores of Przewalski's horses in Hortobagy National Park, Hungary.
Nat. Conserv. Res. 4 (Suppl.), 31-40, 2019.
Journal metrics:
Q2 Agricultural and Biological Sciences (miscellaneous)
Q3 Earth and Planetary Sciences (miscellaneous)
Q3 Ecology
Q3 Nature and Landscape Conservation
9.
Penyige, A., Márton, É., Soltész, B., Szilágyi, M., Póka, R., Lukács, J., Széles, L., Nagy, B.: Circulating miRNA Profiling in Plasma Samples of Ovarian Cancer Patients.
Int. J. Mol. Sci. 20 (18), E4533, (article identifier: 4533), 2019.
Journal metrics:
Q2 Catalysis
Q1 Computer Science Applications
Q1 Inorganic Chemistry
Q1 Medicine (miscellaneous)
Q2 Molecular Biology
Q1 Organic Chemistry
Q1 Physical and Theoretical Chemistry
Q1 Spectroscopy
10.
Horváth, A., Dániel, B., Széles, L., Cuaranta-Monroy, I., Czimmerer, Z., Ozgyin, L., Steiner, L., Kiss, M., Simándi, Z., Póliska, S., Giannakis, N., Raineri, E., Gut, I. G., Nagy, B., Nagy, L.: Labelled regulatory elements are pervasive features of the macrophage genome and are dynamically utilized by classical and alternative polarization signals.
Nucleic Acids Res. 47 (6), 2778-2792, 2019.
Journal metrics:
D1 Genetics
11.
Piaszyk-Borychowska, A., Széles, L., Csermely, A., Chiang, H. C., Wesoly, J., Lee, C. K., Nagy, L., Bluyssen, H. A. R.: Signal Integration of IFN-I and IFN-II With TLR4 Involves Sequential Recruitment of STAT1-Complexes and NFkB to Enhance Pro-inflammatory Transcription.
Front. Immunol. 10, 1-20, (article identifier: 1253), 2019.
Journal metrics:
Q1 Immunology
Q1 Immunology and Allergy
2015
12.
Rühl, R., Krzyżosiak, A., Niewiadomska-Cimicka, A., Rochel, N., Széles, L., Vaz, B., Wietrzych-Schindler, M., Álvarez, S., Szklenár, M., Nagy, L., de Lera, Á. R., Krężel, W.: 9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice.
PLoS Genet. 11 (6), e1005213-, 2015.
Journal metrics:
D1 Cancer Research
D1 Ecology, Evolution, Behavior and Systematics
D1 Genetics
D1 Genetics (clinical)
D1 Molecular Biology
13.
Széles, L., Meissner, F., Dunand-Sauthier, I., Thelemann, C., Hersch, M., Singovski, S., Haller, S., Gobet, F., Fuertes Marraco, S. A., Mann, M., Garcin, D., Acha-Orbea, H., Reith, W.: TLR3-Mediated CD8+ Dendritic Cell Activation Is Coupled with Establishment of a Cell-Intrinsic Antiviral State.
J. Immunol. 195 (3), 1025-1033, 2015.
Journal metrics:
Q1 Immunology
2013
14.
Nagy, Z. S., Ross, J. A., Rodriguez, G., Bálint, B. L., Széles, L., Nagy, L., Kirken, R. A.: Genome Wide Mapping Reveals PDE4B as an IL-2 Induced STAT5 Target Gene in Activated Human PBMCs and Lymphoid Cancer Cells.
PLoS One. 8 (2), e57326, 2013.
Journal metrics:
D1 Agricultural and Biological Sciences (miscellaneous)
Q1 Biochemistry, Genetics and Molecular Biology (miscellaneous)
D1 Medicine (miscellaneous)
15.
Gyöngyösi, A., Szatmári, I., Pap, A., Dezső, B., Pos, Z., Széles, L., Varga, T., Nagy, L.: RDH10, RALDH2, and CRABP2 are required components of PPARγ-directed ATRA synthesis and signaling in human dendritic cells.
J. Lipid Res. 54 (9), 2458-2474, 2013.
Journal metrics:
Q1 Biochemistry
Q1 Cell Biology
D1 Endocrinology
2012
16.
Fuertes Marraco, S. A., Grosjean, F., Duval, A., Rosa, M., Lavanchy, C., Ashok, D., Haller, S., Otten, L. A., Steiner, Q. G., Descombes, P., Luber, C. A., Meissner, F., Mann, M., Széles, L., Reith, W., Acha-Orbea, H.: Novel Murine Dendritic Cell Lines: a Powerful Auxiliary Tool for Dendritic Cell Research.
Front. Immunol. 3, 1-25, 2012.
Journal metrics:
Q3 Immunology
Q2 Immunology and Allergy
17.
Nagy, L., Szántó, A., Szatmári, I., Széles, L.: Nuclear hormone receptors enable macrophages and dendritic cells to sense their lipid environment and shape their immune response.
Physiol. Rev. 92 (2), 739-789, 2012.
Journal metrics:
D1 Medicine (miscellaneous)
D1 Molecular Biology
D1 Physiology
D1 Physiology (medical)
2011
18.
Póliska, S., Csánky, E., Szántó, A., Szatmári, I., Meskó, B., Széles, L., Dezső, B., Scholtz, B., Podani, J., Kilty, I., Takács, L., Nagy, L.: Chronic Obstructive Pulmonary Disease-Specific Gene Expression Signatures of Alveolar Macrophages as well as Peripheral Blood Monocytes Overlap and Correlate with Lung Function.
Respiration. 81 (6), 499-510, 2011.
Journal metrics:
Q1 Pulmonary and Respiratory Medicine
19.
Bálint, B. L., Meskó, B., Nagy, L., Lányi, Á., Scholtz, B., Széles, L., Varga, T.: Molekuláris medicina alapjai.
Debreceni Egyetem, Debrecen, 85 p., 2011.
20.
Nakken, B., Varga, T., Szatmári, I., Széles, L., Gyöngyösi, A., Illarionov, P. A., Dezső, B., Gogolák, P., Rajnavölgyi, É., Nagy, L.: Peroxisome proliferator-activated receptor [gamma]-regulated cathepsin D is required for lipid antigen presentation by dendritic cells.
J. Immunol. 187 (1), 240-247, 2011.
Journal metrics:
D1 Immunology
2010
21.
Töröcsik, D., Baráth, M., Benkő, S., Széles, L., Dezső, B., Póliska, S., Hegyi, Z., Homolya, L., Szatmári, I., Lányi, Á., Nagy, L.: Activation of liver X receptor sensitizes human dendritic cells to inflammatory stimuli.
J. Immunol. 184 (10), 5456-5464, 2010.
Journal metrics:
D1 Immunology
22.
Töröcsik, D., Széles, L., Paragh, G. J., Rákosy, Z., Bárdos, H., Nagy, L., Balázs, M., Inbal, A., Ádány, R.: Factor XIII-A is involved in the regulation of gene expression in alternatively activated human macrophages.
Thromb. Haemost. 104 (4), 709-717, 2010.
Journal metrics:
Q1 Hematology
23.
Széles, L., Póliska, S., Nagy, G., Szatmári, I., Szántó, A., Pap, A., Lindstedt, M., Santegoets, S. J. A. M., Rühl, R., Dezső, B., Nagy, L.: Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.
Mol. Endocrinol. 24 (11), 2218-2231, 2010.
Journal metrics:
D1 Endocrinology
D1 Medicine (miscellaneous)
Q1 Molecular Biology
24.
Szántó, A., Bálint, B. L., Nagy, Z., Barta, E., Dezső, B., Pap, A., Széles, L., Póliska, S., Oros, M., Evans, R. M., Barak, Y., Schwabe, J., Nagy, L.: STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPAR[gamma]-Regulated Gene Expression in Macrophages and Dendritic Cells.
Immunity. 3 (5), 699-712, 2010.
Journal metrics:
D1 Immunology
D1 Immunology and Allergy
D1 Infectious Diseases
2009
25.
Széles, L., Keresztes, G., Töröcsik, D., Balajthy, Z., Krenács, L., Póliska, S., Steinmeyer, A., Zuegel, U., Pruenster, M., Rot, A., Nagy, L.: 1,25 dihidroxyvitamin D3 Is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype.
J. Immunol. 182 (4), 2047-2083, 2009.
Journal metrics:
D1 Immunology
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