Regioselective Suzuki-Miyaura cross-coupling reactions of the bis(triflate) of 4,7-dihydroxycoumarin

Khaddour, Z., Akrawi, O. A., Suleiman, A. S., Patonay, T., Villinger, A., Langer, P.: Regioselective Suzuki-Miyaura cross-coupling reactions of the bis(triflate) of 4,7-dihydroxycoumarin.
Tetrahedron Lett. 55 (32), 4421-4423, 2014.

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Q2 Biochemistry

Q2 Drug Discovery

Q2 Organic Chemistry

title:

Regioselective Suzuki-Miyaura cross-coupling reactions of the bis(triflate) of 4,7-dihydroxycoumarin

authors:

Khaddour, Zien
Akrawi, Omer A.
Suleiman, Ali S.
Patonay Tamás
Villinger, Alexander
Langer, Peter

published:

2014

type:

article

genre:

research article/review article

journal:

Tetrahedron Letters (ISSN: 0040-4039)

language:

English

HAC:

Natural Sciences, Chemical Sciences

subjects:

Catalysis, Suzuki-Miyaura reaction, Regioselectivity, Palladium, Heterocycles

abstract:

Arylated coumarins were prepared by site-selective Suzuki-Miyaura cross-coupling reaction of the bis(triflate) of 4,7-dihydroxycoumarin. The reactions proceeded by initial attack to the sterically more hindered position, due to electronic reasons.