Synthesis of Benzopyran-Fused Flavone Derivatives via Microwave-Assisted Intramolecular C-H Activation

Sipos, Z., Kónya, K.: Synthesis of Benzopyran-Fused Flavone Derivatives via Microwave-Assisted Intramolecular C-H Activation.
Synthesis. 50 (08), 1610-1620, 2018.

doi DEA WoS Scopus

Folyóirat-mutatók:

Q2 Catalysis

Q1 Organic Chemistry

cím:

Synthesis of Benzopyran-Fused Flavone Derivatives via Microwave-Assisted Intramolecular C-H Activation

szerzők:

Sipos Zoltán
Kónya Krisztina

kiadás éve:

2018

típus:

folyóiratcikk

műfaj:

idegen nyelvű folyóiratközlemény külföldi lapban

folyóirat:

Synthesis (ISSN: 0039-7881)

nyelv:

angol

MAB:

természettudományok, kémiai tudományok

tárgyszavak:

flavones, C-H bond activation, palladium, intramolecular direct arylation, microwave chemistry

absztrakt:

A microwave-assisted intramolecular direct arylation method for the synthesis of benzopyran-fused flavone derivatives containing natural flavone backbones is described. Different polyalkoxy flavones were synthesized and functionalized with 2-bromobenzyl bromide. The resulting compounds were subjected to palladium-catalyzed intramolecular direct arylation reactions supported by microwave irradiation to produce fused tetracyclic flavones. In the case of the 7-substituted chrysin derivative, the regioselectivity of the coupling was also examined.

pályázatok:

GINOP-2.3.2-15-2016-00008